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Why is this drug prescribed: Imitrex is prescribed for the treatment of a migraine attack with or without the presence of an aura (visual disturbances, usually sensations of halos or flickering lights, which precede an attack). The injectable form is also used to relieve cluster headache attacks. (Cluster headaches come on in waves, then disappear for long periods of time. They are limited to one side of the head, and occur mainly in men.) Imitrex cuts headaches short. It will not reduce the number of attacks you experience.

Most important fact about this drug: Imitrex should be used only to treat an acute, classic migraine attack or a cluster headache. It should not be used for certain unusual types of migraine.

How should you take this medication: Imitrex should be taken as soon as your symptoms appear, but may be used at any time during an attack. It is available in three forms: injection, tablets, and nasal spray. Imitrex injection is administered just below the skin with an autoinjector (self-injection device). Choose a site where the skin is thick enough to take the full length of the needle (1/4 inch). Avoid injecting Imitrex into a muscle or a vein. Your doctor should instruct you on how to use the autoinjector and how to dispose of the empty syringes. You should also read the instruction pamphlet that comes with the medication. You can take a second injection if your headache returns; however, never take more than 2 injections within 24 hours, and be sure to wait 1 hour between doses. Imitrex tablets should be swallowed whole, with liquid. If you have had no relief 2 hours after taking Imitrex Tablets, you may take a second dose of up to 100 milligrams, if your doctor advises it. If the headache returns, you may take additional doses at intervals of at least 2 hours. You should not take more than 300 milligrams in one day. If your headache returns after you have had an Imitrex Injection, you may take single Imitrex Tablets, at intervals of at least 2 hours, up to a maximum of 200 milligrams in a day. Imitrex nasal spray is packaged in single-dose bottles containing either 5 or 20 milligrams of the drug. The usual dosage is a single spray in one nostril. If the headache returns, you may repeat the dose once after 2 hours. Do not take more than 40 milligrams a day. –If you miss a dose… Imitrex is not for regular use. Take it only during an attack. –Storage instructions… Store Imitrex away from heat and light, at room temperature, in the case provided. If your medication has expired (the expiration date is printed on the treatment pack), throw it away as instructed, but keep the autoinjector. If your doctor decides to stop your treatment, do not keep any leftover medicine unless your doctor tells you to. Throw away your medicine as instructed.

Amaryl is an oral medication used to treat type 2 (non-insulin-dependent) diabetes when diet and exercise alone fail to control abnormally high levels of blood sugar. Like other diabetes drugs classified as sulfonylureas, Amaryl lowers blood sugar by stimulating the pancreas to produce more insulin. Amaryl is often prescribed along with the insulin-boosting drug Glucophage. It may also be used in conjunction with insulin and other diabetes drugs. 

Always remember that Amaryl is an aid to, not a substitute for, good diet and exercise. Failure to follow a sound diet and exercise plan may diminish the results of Amaryl and can lead to serious complications such as dangerously high or low blood sugar levels. Remember, too, that Amaryl is not an oral form of insulin, and cannot be used in place of insulin. 

Do not take more or less of this medication than directed by your doctor. Amaryl should be taken with breakfast or the first main meal.

If you miss a dose… 

Take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time. 

Storage instructions… 

Amaryl should be stored at room temperature in a well-closed container. 

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Amaryl. 

More common side effects may include:
Anemia and other blood disorders, blurred vision, diarrhea, dizziness, headache, itching, liver problems and jaundice, muscle weakness, nausea, sensitivity to light, skin rash and eruptions, stomach and intestinal pain, vomiting

 Amaryl, like all oral antidiabetics, can result in hypoglycemia (low blood sugar). The risk of hypoglycemia can be increased by missed meals, alcohol, fever, injury, infection, surgery, excessive exercise, and the addition of other medications such as Glucophage or insulin. To avoid hypoglycemia, closely follow the dietary and exercise regimen suggested by your doctor. 

Avoid Amaryl if you have ever had an allergic reaction to it. 

Do not take Amaryl to correct diabetic ketoacidosis (a life-threatening medical emergency caused by insufficient insulin and marked by excessive thirst, nausea, fatigue, and fruity breath). This condition should be treated with insulin. 

It’s possible that drugs such as Amaryl may lead to more heart problems than diet treatment alone, or treatment with diet and insulin. If you have a heart condition, you may want to discuss this with your doctor. 

When taking Amaryl, you should check your blood and urine regularly for abnormally high sugar (glucose) levels. The effectiveness of any oral antidiabetic, including Amaryl, may decrease with time. This may occur because of either a diminished responsiveness to the medication or a worsening of the diabetes. 

Even people with well-controlled diabetes may find that stress such as injury, infection, surgery, or fever triggers a loss of control. If this happens, your doctor may recommend that you add insulin to your treatment with Amaryl or that you temporarily stop taking Amaryl and use insulin instead.